Throat painA variety of pulmonary and ear, nose, and throat ENT symptoms and disorders are considered to be extraoesophageal manifestations of gastro-oesophageal reflux disease GORD. These extraoesophageal manifestations include asthma, chronic cough, laryngeal disorders, and various ENT symptoms. Recent studies have established that GORD underlies or contributes to chronic sinusitis, chronic otitis media, paroxysmal laryngospasm, excessive throat phlegm, and postnasal drip. Traditionally, management of extraoesophageal GORD manifestations relies on prolonged empiric therapy with high doses of proton pump inhibitors PPI , followed by pH monitoring under PPI in refractory cases. Recent studies found no benefit of empiric long term high dose PPI therapy. The diagnostic yield of endoscopy in extraoesophageal GORD manifestations seems higher than previously appreciated while pH monitoring under PPI therapy has a low yield.
November is a time of colds and flu. November also tends to be dull and damp. Add the dryness of heated rooms and the spread of bacteria and viruses is a certainty. One of the first sypmtoms of a cold is Pregnancy Headache Swelling pain in the throat. Sore throat is also called pharyngitis. The throat includes the tonsilsoesophagus, larynx or voice box, epiglottis, vocal cordsand trachea or windpipe.
Globus, chronic cough, mucous obstruction and hoarseness are frequently interpreted and classified as manifestation of extraesophageal reflux EER or laryngopharyngeal reflux LPR. The patients were stratified into 3 groups: The response to APC varied between the quality of symptoms and was most frequently seen in globus, swallowing difficulty and mucous obstruction. The magnitude of symptom reduction was highest in heartburn, sore throat, and globus. The response to APC was comparable between the three groups of patients irrespective of GERD and the presence or absence of reflux symptoms. However, we could not demonstrate a clinical or functional parameter that differentiated between responders and non-responders to APC or could predict the response to APC. Die Patienten wurden in 3 Gruppen stratifiziert:
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